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KMID : 0882419970520030419
Korean Journal of Medicine
1997 Volume.52 No. 3 p.419 ~ p.424
A Case of Multifocal Cerebral Infarction Associated with Idiopathic Hypereosinophilic Syndrome



Kang Heung-Sun
Choue Chung-Whee
Kim Kwon-Sam
Kim Myung-Shick
Song Jung-Sang
Bae Jong-Hoa
Abstract
The idiopathic hypereosinophilic syndrome represent a heterogenous group of disorders with common features of prolonged eosinophilia of an undetectable cause and organ system dysfunction. Recently, we experienced a case of idiopathic hypereosinophilic syndrome with multifocal cerebral infarction. The patient was 33-year-old male and visited our hospital with right upper extremity weakness and headache. The blood eosinophil counts were 8,316/mma and the marrow showed eosinophils were predominant and in mature forms The two-dimensional echocardiogram showed hyperechoic density at left ventricular apical wall without thrombus formation. Multifocal infarctions were seen at left cerebellar hemisphere, left thalamus, right frontal lobe and left periventricular white matter on brain MRI scan. No cause for hypereosinophilia was found. He was treated with prednisone and hydroxyurea.
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